Article
Influence of the Obesity Phenotype on the Adequacy of Antibiotic Prophylaxis with Cefoxitin for Obese Patients Undergoing Bariatric Surgery: Lessons Learnt and Future Considerations.
European journal of drug metabolism and pharmacokinetics - 1 Jul 2021
Belveyre Thibaut, Scala-Bertola Julien, Esposito Mathieu, Luc Amandine, Lipman Jeffrey, Novy Emmanuel
Abstract excerpt
BACKGROUND AND OBJECTIVES: A high inter-individual variability in pharmacokinetic parameters in obese patients is observed. The objective of this study was to evaluate the effect of obesity parameters on the pharmacokinetics of cefoxitin administered for antibiotic prophylaxis during bariatric surgery. METHODS: This a secondary analysis of a pharmacokinetic study involving 174 obese patients scheduled for...
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