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Article

DEP-induced ZEB2 promotes nasal polyp formation via epithelial-to-mesenchymal transition

3 May 2021

Abstract excerpt

BACKGROUND: Diesel exhaust particles (DEPs) are associated with the prevalence and exacerbation of allergic respiratory diseases, including allergic rhinitis and allergic asthma. However, DEP-induced mechanistic pathways promoting upper airway disease and their clinical implications remain unclear. OBJECTIVE: We sought to investigate the mechanisms by which DEP exposure contributes to nasal polyposis using...

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PMID: 33957165
DOI: 10.1016/j.jaci.2021.04.024

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