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BNT162b2 mRNA COVID‐19 vaccine induces antibodies of broader cross‐reactivity than natural infection, but recognition of mutant viruses is up to 10‐fold reduced

5 May 2021

Abstract excerpt

The receptor binding domain (RBD) of SARS-CoV-2 spike (S) glycoprotein, which is involved in virus attachment and cell entry, is the primary target for neutralizing antibodies.1 Immunization against full-length S or parts of it may result in more potent and longer-lasting antibody responses than natural viral infection.2 Therefore, global vaccination programs based on induction of neutralizing antibodies are the...

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PMID: 33948956
DOI: 10.1111/all.14893

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