Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MR1 overexpression correlates with poor clinical prognosis in glioma patients

1 Jan 2021

Abstract excerpt

Abstract Background Glioblastoma is the most common adult primary brain tumor with near-universal fatality. Major histocompatibility complex (MHC) class I molecules are important mediators of CD8 activation and can be downregulated by cancer cells to escape immune surveillance. MR1 is a nonclassical MHC-I-like molecule responsible for the activation of a subset of T cells. Although high levels of MR1 expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glioma Diagnosis and Treatment
Share to Immune Cell Function and Interaction
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33948562
DOI: 10.1093/noajnl/vdab034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MR1 overexpression correlates with poor clinical prognosis in glioma patientsPMID 33948562Read ↗

Molecular and Clinical Characteristics Associated with Elevated TREM1 and its Emergence as a Prognostic Biomarker in GliomasSemantic proximity Read ↗

MXRA5 Is a Novel Immune-Related Biomarker That Predicts Poor Prognosis in GliomaSemantic proximity Read ↗

LRRFIP1, an epigenetically regulated gene, is a prognostic biomarker and predicts malignant phenotypes of glioma.Semantic proximity Read ↗

Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapySemantic proximity Read ↗

Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiformeSemantic proximity Read ↗

<i>MUC1</i>and<i>MUC4</i>expression are inversely correlated and trigger immunological response and transport pathways in gliomasSemantic proximity Read ↗

MUL1, an Immune Chemokine-Related Gene, Regulates Glioma Cell Proliferation and Migration: Insights from Functional and Mechanistic StudiesSemantic proximity Read ↗

BZW1 as an oncogene is associated with patient prognosis and the immune microenvironment in gliomaSemantic proximity Read ↗

CMTM6 overexpression is associated with molecular and clinical characteristics of malignancy and predicts poor prognosis in gliomasSemantic proximity Read ↗

Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity and Restricted Cytotoxic Effector Cell Trafficking and Activation During Malignant Progression in GliomaSemantic proximity Read ↗

Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1.Semantic proximity Read ↗

Molecular and clinical characterization of CD163 expression via large-scale analysis in gliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.