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Article

LINGO3 regulates mucosal tissue regeneration and promotes TFF2 dependent recovery from colitis

3 May 2021

Abstract excerpt

Aim: Recovery of damaged mucosal surfaces following inflammatory insult requires diverse regenerative mechanisms that remain poorly defined. Previously, we demonstrated that the reparative actions of Trefoil Factor 3 (TFF3) depend upon the enigmatic receptor, leucine rich repeat and immunoglobulin-like domain containing nogo receptor 2 (LINGO2). This study examined the related orphan receptor LINGO3 in the...

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PMID: 33941035
DOI: 10.1080/00365521.2021.1917650

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