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Article

Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Dec 2021

Guo Jing, Brickman Adam M, Manly Jennifer J, Reitz Christiane, Schupf Nicole, Mayeux Richard P, Gu Yian

Abstract excerpt

INTRODUCTION: There is limited and inconsistent reporting on the association between Life's Simple 7 (LS7) and dementia in the elderly population. METHODS: Based on the Washington Heights-Inwood Columbia Aging Project (WHICAP), LS7 scores were estimated to assess cardiovascular health status. Associations between LS7 scores and incident dementia were investigated by Cox proportional hazards models. RESULTS: Among...

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Identifiers

PMID: 33938146
DOI: 10.1002/alz.12359
PMCID: PMC8560654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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