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Article

Enteric mesenchymal cells support the growth of postnatal enteric neural stem cells

8 May 2021

Abstract excerpt

Abstract Interplay between embryonic enteric neural stem cells (ENSCs) and enteric mesenchymal cells (EMCs) in the embryonic gut is essential for normal development of the enteric nervous system. Disruption of these interactions underlies the pathogenesis of intestinal aganglionosis in Hirschsprung disease (HSCR). ENSC therapy has been proposed as a possible treatment for HSCR, but whether the survival and...

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Share to Congenital Anomalies and Fetal Surgery
Share to Congenital gastrointestinal and neural anomalies
Share to Intestinal Malrotation and Obstruction Disorders

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PMID: 33938072
DOI: 10.1002/stem.3388

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