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Article

Exposure to GDNF Enhances the Ability of Enteric Neural Progenitors to Generate an Enteric Nervous System.

Stem cell reports - 14 Feb 2017

McKeown Sonja J, Mohsenipour Mitra, Bergner Annette J, Young Heather M, Stamp Lincon A

Abstract excerpt

Cell therapy is a promising approach to generate an enteric nervous system (ENS) and treat enteric neuropathies. However, for translation to the clinic, it is highly likely that enteric neural progenitors will require manipulation prior to transplantation to enhance their ability to migrate and generate an ENS. In this study, we examine the effects of exposure to several factors on the ability of ENS progenitors,...

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Source

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Identifiers

PMID: 28089669
DOI: 10.1016/j.stemcr.2016.12.013
PMCID: PMC5312076

Genes

GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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