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Article

Mast cell tryptases in allergic inflammation and immediate hypersensitivity.

Current opinion in immunology - 1 Oct 2021

Lyons Jonathan J, Yi Tangsheng

Abstract excerpt

Dysregulated mast cell-mediated inflammation and/or activation have been linked to a number of human diseases, including asthma, anaphylaxis, chronic spontaneous urticaria, and mast cell activation syndromes. As a major mast cell granule protein, tryptase is a biomarker commonly used in clinical practice to diagnose mast cell-associated disorders and -mediated reactions, but its mechanistic roles in disease...

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Identifiers

PMID: 33932709
DOI: 10.1016/j.coi.2021.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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