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Article

Tryptase: genetic and functional considerations.

Allergologia et immunopathologia - 1 Jan 2000

Hernández-Hernández L, Sanz C, García-Solaesa V, Padrón J, García-Sánchez A, Dávila I, Isidoro-García M, Lorente F

Abstract excerpt

Tryptase is one of the main proteases located in the secretory granules of the mast cells, and is released through degranulation. It is therefore assumed to play an important role in inflammatory and allergic processes. Four genes are known to encode for these enzymes, with different alleles that give rise to different types of tryptases. The term "tryptase" generally refers to β-tryptase, which in vivo is a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22770587
DOI: 10.1016/j.aller.2012.04.004

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