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Deciphering the Variants Located in the MIR196A2, MIR146A, and MIR423 with Type-2 Diabetes Mellitus in Pakistani Population.

Genes - 28 Apr 2021

Khan Muhammad Sohail, Rahman Bashir, Haq Taqweem Ul, Jalil Fazal, Khan Bilal Muhammad, Maodaa Saleh N, Al-Farraj Saleh A, El-Serehy Hamed A, Shah Aftab Ali

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNA molecules that control the post-transcriptional gene expression. They play a pivotal role in the regulation of important physiological processes. Variations in miRNA genes coding for mature miRNA sequences have been implicated in several diseases. However, the association of variants in miRNAs genes with Type 2 Diabetes Mellitus (T2DM) in the Pakistani population is...

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PMID: 33925232
DOI: 10.3390/genes12050664
PMCID: PMC8146332

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