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Article

Effect of Hydrocortisone on Angiotensinogen (AGT) Mutation-Causing Autosomal Recessive Renal Tubular Dysgenesis.

Cells - 1 Apr 2021

Tseng Min-Hua, Huang Shih-Ming, Konrad Martin, Huang Jing-Long, Shaw Steven W, Tian Ya-Chung, Chueh Ho-Yen, Fan Wen-Lang, Wu Tai-Wei, Ding Jhao-Jhuang, Chiang Ming-Chou, Lin Shih-Hua

Abstract excerpt

We has identified a founder homozygous E3_E4 del: 2870 bp deletion + 9 bp insertion in AGT gene encoding angiotensinogen responsible for autosomal recessive renal tubular dysgenesis (ARRTD) with nearly-fatal outcome. High-dose hydrocortisone therapy successfully rescued one patient with an increased serum Angiotensinogen (AGT), Ang I, and Ang II levels. The pathogenesis of ARRTD caused by this AGT mutation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33916187
DOI: 10.3390/cells10040782
PMCID: PMC8065467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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