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Article

Genome-wide association study of antipsychotic-induced sinus bradycardia in Chinese schizophrenia patients.

PloS one - 1 Jan 2021

Weng Saizheng, Wang Bo, Li Mo, Chao Shan, Lin Ruiqian, Zheng Rongyan, Yu Yinliang, Guo Shaonan, Lin Xianhao

Abstract excerpt

Second-generation antipsychotics (SGAs) play a critical role in current treatment of schizophrenia (SCZ). It has been observed that sinus bradycardia, rare but in certain situations life threatening adverse drug reaction, can be induced by SGAs across different schizophrenia populations. However, the roles of genetic factors in this phenomenon have not been studied yet. In the present study, a genome-wide...

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PMID: 33914752
DOI: 10.1371/journal.pone.0249997
PMCID: PMC8084176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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