Article
MYOD1 as a prognostic indicator in rhabdomyosarcoma.
Pediatric blood & cancer - 1 Sept 2021
Ahmed Atif A, Habeebu Sultan, Farooqi Midhat S, Gamis Alan S, Gonzalez Elizabeth, Flatt Terrie, Sherman Ashley, Surrey Lea, Arnold Michael A, Conces Miriam, Koo Selene, Dioufa Nikolina, Barr Frederic G, Tsokos Maria G
Abstract excerpt
BACKGROUND/OBJECTIVES: Rhabdomyosarcoma (RMS) is characterized by the expression of the myogenic regulatory protein MYOD1. Histologic types include alveolar, embryonal (ERMS), and spindle cell sclerosing RMS (SRMS). SRMS harbors MYOD1 mutations in a subset of adult cases in association with poor prognosis. DESIGN/METHODS: To study the level of MYOD1 protein expression and its clinical significance, we have...
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