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Article

Functional and Genetic Landscape of Complement Dysregulation Along the Spectrum of Thrombotic Microangiopathy and its Potential Implications on Clinical Outcomes

6 Feb 2021

Abstract excerpt

Introduction The syndromes of thrombotic microangiopathy (TMA) are diverse and represent severe endothelial damage caused by various mechanisms. The complement system plays a major role in a subset of patients with TMA, and its recognition is of clinical importance because it guides choice and duration of treatment. Methods We studied a well-defined cohort of patients with TMA and hypothesized that assessment of...

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Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33912760
DOI: 10.1016/j.ekir.2021.01.034

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