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Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases

12 Apr 2021

Abstract excerpt

Recent studies have revealed that colorectal cancer (CRC) displays intratumor genetic heterogeneity, and that the cancer microenvironment plays an important role in the proliferation, invasion and metastasis of CRC. The present study performed genomic analysis on paired primary CRC and synchronous colorectal liver metastasis (CRLM) tissues collected from 22 patients using whole-exome sequencing, cancer gene...

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Identifiers

PMID: 33907576
DOI: 10.3892/ol.2021.12727

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