The Pan-Immune-Inflammation Value in microsatellite instability-high metastatic colorectal cancer patients treated with immune checkpoint inhibitors.

doi:10.1016/j.ejca.2021.03.043

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Article

The Pan-Immune-Inflammation Value in microsatellite instability-high metastatic colorectal cancer patients treated with immune checkpoint inhibitors.

European journal of cancer (Oxford, England : 1990) - 1 Jun 2021

Corti Francesca, Lonardi Sara, Intini Rossana, Salati Massimiliano, Fenocchio Elisabetta, Belli Carmen, Borelli Beatrice, Brambilla Marta, Prete Alessandra A, Quarà Virginia, Antista Maria, Fassan Matteo, Morano Federica, Spallanzani Andrea, Ambrosini Margherita, Curigliano Giuseppe, de Braud Filippo, Zagonel Vittorina, Fucà Giovanni, Pietrantonio Filippo

Abstract excerpt

BACKGROUND: Immune checkpoint inhibitors (ICIs) yielded unprecedented efficacy in patients with microsatellite instability (MSI)-high metastatic colorectal cancer (mCRC). Since the Pan-Immune-Inflammation Value (PIV) is a blood-based biomarker with prognostic usefulness in mCRC, it might predict clinical outcomes and primary resistance to ICIs. METHODS: We retrospectively analysed the association of PIV and its...

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PMID: 33901794
DOI: 10.1016/j.ejca.2021.03.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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