Interferon gamma +874T/A polymorphism is associated with susceptibility to active pulmonary tuberculosis development in Tunisian patients.

doi:10.1089/dna.2010.1157

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Article

Interferon gamma +874T/A polymorphism is associated with susceptibility to active pulmonary tuberculosis development in Tunisian patients.

DNA and cell biology - 1 Jun 2011

Ben Selma Walid, Harizi Hedi, Bougmiza Iheb, Hannachi Naila, Ben Kahla Imen, Zaieni Radhia, Boukadida Jalel

Abstract excerpt

Interferon gamma (IFN-γ) is a key cytokine involved mainly in the defense against intracellular pathogens such as Mycobacterium tuberculosis. Given its key role in the control of tuberculosis (TB), in the present article we have investigated a possible association between IFN-γ gene single-nucleotide polymorphism linked to high and low producer phenotypes (IFN-γ [+874T(high) → A(low)]) (rs2430561) and risk...

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PMID: 21332391
DOI: 10.1089/dna.2010.1157

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Interferon gamma +874T/A polymorphism is associated with susceptibility to active pulmonary tuberculosis development in Tunisian patients.PMID 21332391Read ↗

Functional polymorphism of interferon-γ (IFN-γ) gene +874T/A polymorphism is associated with pulmonary tuberculosis in Zahedan, Southeast Iran.Semantic proximity Read ↗

Interferon-γ (+874 T/A) and interleukin-10 (-1082 G/A) genes polymorphisms are associated with active tuberculosis in the Algerian population of Oran's city.Semantic proximity Read ↗

The +874T/A polymorphism in the interferon-γ gene and tuberculosis risk: an update by meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms of IFNγ (+874 A/T) and IFNγR1 (-56 C/T) in Iranian patients with TB.Semantic proximity Read ↗

IFNG +874T/A polymorphism and cytokine plasma levels are associated with susceptibility to Mycobacterium tuberculosis infection and clinical manifestation of tuberculosis.Semantic proximity Read ↗

Association of polymorphism +874 A/T of interferon-γ and susceptibility to the development of tuberculosis: meta-analysis.Semantic proximity Read ↗

A single nucleotide polymorphism in the interferon-γ gene (IFNG +874 T/A) is associated with susceptibility to tuberculosisSemantic proximity Read ↗

Ethnicity based comprehensive evaluation of polymorphism in interferon-gamma gene and its association with pulmonary and extra-pulmonary tuberculosis risk: An updated trial sequential meta-analysis.Semantic proximity Read ↗

Association of IFN-γ +874 A/T SNP and hypermethylation of the -53 CpG site with tuberculosis susceptibility.Semantic proximity Read ↗

Interferon-gamma gene+874T-A polymorphism is associated with tuberculosis and gamma interferon response.Semantic proximity Read ↗

Role of IFN-gamma +874 T/A single nucleotide polymorphism in the tuberculosis outcome among Brazilians subjects.Semantic proximity Read ↗

Association between IFNGR1 gene polymorphisms and tuberculosis susceptibility: A meta-analysis.Semantic proximity Read ↗

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