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Emerging variants of concern in SARS-CoV-2 membrane protein: a highly conserved target with potential pathological and therapeutic implications.

Emerging microbes & infections - 1 Dec 2021

Shen Lishuang, Bard Jennifer Dien, Triche Timothy J, Judkins Alexander R, Biegel Jaclyn A, Gai Xiaowu

Abstract excerpt

Mutations in the SARS-CoV-2 Membrane (M) gene are relatively uncommon. The M gene encodes the most abundant viral structural protein, and is implicated in multiple viral functions, including initial attachment to the host cell via heparin sulphate proteoglycan, viral protein assembly in conjunction with the N and E genes, and enhanced glucose transport. We have identified a recent spike in the frequency of...

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Identifiers

PMID: 33896413
DOI: 10.1080/22221751.2021.1922097
PMCID: PMC8118436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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