Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations.

doi:10.1038/s41598-024-68678-z

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Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations.

Scientific reports - 30 Jul 2024

Selvavinayagam Sivaprakasam T, Sankar Sathish, Yong Yean K, Murugesan Amudhan, Suvaithenamudhan Suvaiyarasan, Hemashree Kannan, Rajeshkumar Manivannan, Kumaresan Anandhazhvar, Pandey Ramendra P, Shanmugam Saravanan, Arthydevi Parthiban, Kumar Masilamani Senthil, Gopalan Natarajan, Kannan Meganathan, Cheedarla Narayanaiah, Tan Hong Y, Zhang Ying, Larsson Marie, Balakrishnan Pachamuthu, Velu Vijayakumar, Byrareddy Siddappa N, Shankar Esaki M, Raju Sivadoss

Abstract excerpt

In December 2023, we observed a notable shift in the COVID-19 landscape, when JN.1 omicron emerged as the predominant SARS-CoV-2 variant with a 95% incidence. We characterized the clinical profile, and genetic changes in JN.1, an emerging SARS-CoV-2 variant of interest. Whole genome sequencing was performed on SARS-CoV-2 positive clinical specimens, followed by sequence analysis. Mutations within the spike...

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PMID: 39080396
DOI: 10.1038/s41598-024-68678-z
PMCID: PMC11289243

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