Article
The influence of HLA genotype on the severity of COVID-19 infection.
HLA - 1 Jul 2021
Langton David J, Bourke Stephen C, Lie Benedicte A, Reiff Gabrielle, Natu Shonali, Darlay Rebecca, Burn John, Echevarria Carlos
Abstract excerpt
The impact of COVID-19 varies markedly, not only between individual patients but also between different populations. We hypothesised that differences in human leukocyte antigen (HLA) genes might influence this variation. Using next generation sequencing, we analysed the class I and class II classical HLA genes of 147 individuals of European descent experiencing variable clinical outcomes following COVID-19...
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