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Article

Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.

International journal of nanomedicine - 1 Jan 2021

Sui Min, Xiong Meimei, Li Yuling, Zhou Qiao, Shen Xiaofei, Jia Da, Gou Maling, Sun Qingxiang

Abstract excerpt

INTRODUCTION: Peptides can be rationally designed as non-covalent inhibitors for molecularly targeted therapy. However, it remains challenging to efficiently deliver the peptides into the targeted cells, which often severely affects their therapeutic efficiency. METHODS: Herein, we created a novel non-covalent peptide inhibitor against nuclear export factor CRM1 by a structure-guided drug design method and...

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Identifiers

PMID: 33883894
DOI: 10.2147/IJN.S266398
PMCID: PMC8054660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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