Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive function

20 Apr 2021

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to RNA regulation and disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33879865
DOI: 10.1038/s41380-021-01099-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive functionPMID 33879865Read ↗

Genetic reduction of PERK-eIF2α signaling in dopaminergic neurons drives cognitive and age-dependent motor dysfunctionSemantic proximity Read ↗

Repression of the eIF2α kinase PERK alleviates mGluR-LTD impairments in a mouse model of Alzheimer's diseaseSemantic proximity Read ↗

Neuronal Regulation of eIF2α Function in Health and Neurological Disorders.Semantic proximity Read ↗

Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for DystoniaSemantic proximity Read ↗

Fine‐tuning PERK signaling for neuroprotectionSemantic proximity Read ↗

Oncogenes on my mind: ERK and MTOR signaling in cognitive diseasesSemantic proximity Read ↗

The Potential Role of Protein Kinase R as a Regulator of Age-Related NeurodegenerationSemantic proximity Read ↗

The PERK pathway: beneficial or detrimental for neurodegenerative diseases and tumor growth and cancerSemantic proximity Read ↗

Roles of eIF2Î± kinases in the pathogenesis of Alzheimerâ€™s diseaseSemantic proximity Read ↗

eIF2α phosphorylation evokes dystonia-like movements with D2-receptor and cholinergic origin and abnormal neuronal connectivitySemantic proximity Read ↗

Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.Semantic proximity Read ↗

The mTOR signalling cascade: paving new roads to cure neurological diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.