Article
Heterologous expression implicates a GATA factor in regulation of nitrogen metabolic genes and ion homeostasis in the halotolerant yeast Debaryomyces hansenii.
Eukaryotic cell - 1 Aug 2006
García-Salcedo Raúl, Casamayor Antonio, Ruiz Amparo, González Asier, Prista Catarina, Loureiro-Dias Maria C, Ramos José, Ariño Joaquín
Abstract excerpt
The yeast Debaryomyces hansenii has a remarkable capacity to proliferate in salty and alkaline environments such as seawater. A screen for D. hansenii genes able to confer increased tolerance to high pH when overexpressed in Saccharomyces cerevisiae yielded a single gene, named here DhGZF3, encoding a putative negative GATA transcription factor related to S. cerevisiae Dal80 and Gzf3. Overexpression of this gene...
Topics
- Adenosine Triphosphatases
- Alkalies
- Cation Transport Proteins
- GATA Transcription Factors
- Gene Expression Regulation, Fungal
- Homeostasis
- Hydrogen-Ion Concentration
- Ions
- Mutation
- Nitrogen
- Repressor Proteins
- Saccharomyces cerevisiae