Article
A Tail Fiber Protein and a Receptor-Binding Protein Mediate ICP2 Bacteriophage Interactions with Vibrio cholerae OmpU.
Journal of bacteriology - 8 Jun 2021
Lim Andrea N W, Yen Minmin, Seed Kimberley D, Lazinski David W, Camilli Andrew
Abstract excerpt
ICP2 is a virulent bacteriophage (phage) that preys on Vibrio cholerae. ICP2 was first isolated from cholera patient stool samples. Some of these stools also contained ICP2-resistant isogenic V. cholerae strains harboring missense mutations in the trimeric outer membrane porin protein OmpU, identifying it as the ICP2 receptor. In this study, we identify the ICP2 proteins that mediate interactions with OmpU by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
