Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characteristics of the PI3K/AKT and MAPK/ERK pathways involved in the maintenance of self-renewal in lung cancer stem-like cells

1 Jan 2021

Abstract excerpt

Lung cancer is the leading cause of cancer-related mortality worldwide due to its early asymptomatic and late metastasis. While cancer stem cells (CSCs) may play a vital role in oncogenesis and development of lung cancer, mechanisms underlying CSCs self-renewal remain less clear. In the present study, we constructed a clinically relevant CSCs enrichment recognition model and evaluated the potential functions of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33867839
DOI: 10.7150/ijbs.57871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characteristics of the PI3K/AKT and MAPK/ERK pathways involved in the maintenance of self-renewal in lung cancer stem-like cellsPMID 33867839Read ↗

Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53Semantic proximity Read ↗

Single-Cell Transcriptomics Unveils the Dedifferentiation Mechanism of Lung Adenocarcinoma Stem CellsSemantic proximity Read ↗

Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathwaysSemantic proximity Read ↗

mRNAsi Index: Machine Learning in Mining Lung Adenocarcinoma Stem Cell BiomarkersSemantic proximity Read ↗

E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent mannerSemantic proximity Read ↗

A cancer stemness-related eight-gene signature for predicting prognosis and malignant degree of lung adenocarcinomaSemantic proximity Read ↗

The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy.Semantic proximity Read ↗

Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cellsSemantic proximity Read ↗

Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like PropertiesSemantic proximity Read ↗

Targeting Lung Cancer Stem Cells: Research and Clinical ImpactsSemantic proximity Read ↗

Comparison of tumor biology of two distinct cell sub-populations in lung cancer stem cellsSemantic proximity Read ↗

PI3K/Akt/mTOR signaling pathway in cancer stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.