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Article

Computational analysis of deleterious single nucleotide polymorphisms in catechol O-Methyltransferase conferring risk to post-traumatic stress disorder.

Journal of psychiatric research - 1 Jun 2021

Chitrala Kumaraswamy Naidu, Nagarkatti Prakash, Nagarkatti Mitzi

Abstract excerpt

Post-traumatic stress disorder (PTSD) is one of the prevalent neurological disorder which is drawing increased attention over the past few decades. Major risk factors for PTSD can be categorized into environmental and genetic factors. Among the genetic risk factors, polymorphisms in the catechol-O-methyltransferase (COMT) gene is known to be associated with the risk for PTSD. In the present study, we analysed the...

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Identifiers

PMID: 33865170
DOI: 10.1016/j.jpsychires.2021.03.048
PMCID: PMC8969201

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