Article
Mendelian randomization analyses reveal novel drug targets for anorexia nervosa.
Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2022
Yang Jian, Fan Yajuan, Yan Bin, Zhao Binbin, Qian Li, Gao Fengjie, Ma Qingyan, Yang Lihong, Wang Wei, Bai Ling, Zhu Feng, Ma Xiancang
Abstract excerpt
Among all psychiatric disorders, anorexia nervosa (AN) has the highest mortality rate. However, there is still no pharmacological therapy for AN. The human plasma proteome may be a great cornerstone for the development of new drugs against AN. Here we performed a Mendelian randomization (MR) analysis to identify causal risk proteins for AN. Exposure data were extracted from a large genome-wide association study...
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