Article
Genetically predicted circulating B vitamins in relation to digestive system cancers.
British journal of cancer - 1 Jun 2021
Yuan Shuai, Carter Paul, Vithayathil Mathew, Kar Siddhartha, Mason Amy M, Burgess Stephen, Larsson Susanna C
Abstract excerpt
BACKGROUND: Folate, vitamin B6 and vitamin B12 have been associated with digestive system cancers. We conducted a two-sample Mendelian randomisation study to assess the causality of these associations. METHODS: Two, one and 14 independent single nucleotide polymorphisms associated with serum folate, vitamin B6 and vitamin B12 at the genome-wide significance threshold were selected as genetic instruments....
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