Article
Contribution of XPD and XPF Polymorphisms to Susceptibility of Non-Small Cell Lung Cancer in High-Altitude Areas.
Public health genomics - 1 Jan 2021
Li Miao, Chen Rong, Ji Baoyan, Fan Chunmei, Wang Guanying, Yue Chenli, Li Guoquan
Abstract excerpt
BACKGROUND: We aimed to explore the relation of XPD and XPF variants with non-small cell lung cancer (NSCLC) risk and the effect of these variants on the sensitivity to cisplatin-based chemotherapy among the Chinese Han population in high-altitude areas. METHODS: Eight single-nucleotide polymorphisms (SNPs) in XPD and XPF were genotyped by Agena MassARRAY platform among 506 NSCLC cases and 510 healthy controls....
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