Article
Comprehensive characterization of alternative splicing in renal cell carcinoma.
Briefings in bioinformatics - 2 Sept 2021
Zhang Yangjun, Wu Xiaoliang, Li Jingzhen, Sun Kui, Li Heng, Yan Libin, Duan Chen, Liu Haoran, Chen Ke, Ye Zhangqun, Liu Mugen, Xu Hua
Abstract excerpt
Irregular splicing was associated with tumor formation and progression in renal cell carcinoma (RCC) and many other cancers. By using splicing data in the TCGA SpliceSeq database, RCC subtype classification was performed and splicing features and their correlations with clinical course, genetic variants, splicing factors, pathways activation and immune heterogeneity were systemically analyzed. In this research,...
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