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Article

Mutations in two component system (PhoPQ and PmrAB) in colistin resistant Klebsiella pneumoniae from North Indian tertiary care hospital.

The Journal of antibiotics - 1 Jul 2021

Nirwan Pushpa Kumari, Chatterjee Nirupama, Panwar Rajesh, Dudeja Mridu, Jaggi Namita

Abstract excerpt

Colistin resistance in Gram negative bacteria is mainly attributed to chromosomal mutations in Two Component Systems(TCS) PhoPQ and PmrAB and plasmid-borne genes(mcr and its variants). The aim of this study was to understand the molecular basis of colistin resistance in Klebsiella pneumoniae and determine clonal transmission, in a North Indian tertiary care hospital over a 2.5 year period. Antimicrobial...

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Identifiers

PMID: 33820943
DOI: 10.1038/s41429-021-00417-2

Genes

ST14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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