Association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T and risk of myocardial infarction: a meta-analysis for 8,140 cases and 10,522 controls.

doi:10.1016/j.arcmed.2011.11.009

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Article

Association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T and risk of myocardial infarction: a meta-analysis for 8,140 cases and 10,522 controls.

Archives of medical research - 1 Nov 2011

Xuan Chao, Bai Xiao-Yan, Gao Ge, Yang Qin, He Guo-Wei

Abstract excerpt

BACKGROUND AND AIMS: The methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism has been reported to be associated with myocardial infarction (MI), but results from previous studies are conflicting. The present study aimed at investigating the association between this polymorphism an...

Topics

Case-Control Studies
Female
Gene Frequency
Genetic Association Studies
Humans
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Myocardial Infarction
Polymorphism, Single Nucleotide
Risk Factors
White People

Source

Open in PubMed

Identifiers

PMID: 22154679
DOI: 10.1016/j.arcmed.2011.11.009

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-22154679-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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