Article
Population-Predicted MHC Class II Epitope Presentation of SARS-CoV-2 Structural Proteins Correlates to the Case Fatality Rates of COVID-19 in Different Countries.
International journal of molecular sciences - 5 Mar 2021
Liang Chunguang, Bencurova Elena, Psota Eric, Neurgaonkar Priya, Prelog Martina, Scheller Carsten, Dandekar Thomas
Abstract excerpt
We observed substantial differences in predicted Major Histocompatibility Complex II (MHCII) epitope presentation of SARS-CoV-2 proteins for different populations but only minor differences in predicted MHCI epitope presentation. A comparison of this predicted epitope MHC-coverage revealed for the early phase of infection spread (till day 15 after reaching 128 observed infection cases) highly significant negative...
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