Article
A bioinformatic prediction of antigen presentation from SARS-CoV-2 spike protein revealed a theoretical correlation of HLA-DRB1*01 with COVID-19 fatality in Mexican population: An ecological approach.
Journal of medical virology - 1 Apr 2021
Romero-López José Pablo, Carnalla-Cortés Martha, Pacheco-Olvera Diana L, Ocampo-Godínez Juan Moisés, Oliva-Ramírez Jacqueline, Moreno-Manjón Julia, Bernal-Alferes Brian, López-Olmedo Nancy, García-Latorre Ethel, Domínguez-López María Lilia, Reyes-Sandoval Arturo, Jiménez-Zamudio Luis
Abstract excerpt
SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their restricted HLA Class I and II alleles was performed to obtain immunogenic epitopes and HLA...
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