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Article

Causal Associations between Serum Urea and Cancer: A Mendelian Randomization Study.

Genes - 29 Mar 2021

Sun Yandi, Li Jingjia, Qu Zihao, Yang Ze, Jia Xueyao, Lin Yindan, He Qian, Zhang Lihong, Luo Yan

Abstract excerpt

Urea is largely derived from the urea cycle reactions through hepatic detoxification of free ammonia and cleared by urination, and the serum urea level is a crucial medical indicator for measuring the kidney function in patients with nephropathy; however, investigative revelations pointing to the serum urea level as a risk factor for cancer are very scarce, and relevant studies are restricted by potential biases....

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Identifiers

PMID: 33805346
DOI: 10.3390/genes12040498
PMCID: PMC8066321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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