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Serum Uric Acid Levels and Risk of Eight Site-Specific Cancers: A Mendelian Randomization Study

9 Mar 2021

Abstract excerpt

The relationship between serum uric acid (UA) levels and cancer risk remains controversial. Here, a two-sample Mendelian randomization analysis was performed to identify a causal effect of serum UA levels on cancer risk. Twenty-six single nucleotide polymorphisms strongly associated with serum UA levels were screened as genetic variants from large-scale meta-analysis data of a genome-wide association study of...

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PMID: 33767728
DOI: 10.3389/fgene.2021.608311

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