Death receptors as targets for anti‐cancer therapy

Abstract excerpt

Introduction Death receptor signalling TNF‐R1 signalling CD95 signalling TRAIL‐R signalling Targeting death receptors in cancer therapy Targeting TNF‐R1 Targeting CD95 TRAIL as a target for anti‐cancer therapy Future perspectives Abstract Human tumour cells are characterized by their ability to avoid the normal regulatory mechanisms of cell growth, division and death. The classical chemotherapy aims to kill...

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