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Article

A KCNQ4 c.546C>G Genetic Variant Associated with Late Onset Non-Syndromic Hearing Loss in a Taiwanese Population.

Genes - 27 Oct 2021

Yen Ting-Ting, Chen I-Chieh, Hua Men-Wei, Wei Chia-Yi, Shih Kai-Hsiang, Li Jui-Lin, Lin Ching-Heng, Hsiao Tzu-Hung, Chen Yi-Ming, Jiang Rong-San

Abstract excerpt

Clinical presentation is heterogeneous for autosomal dominant nonsyndromic hearing loss (ADNSHL). Variants of KCNQ4 gene is a common genetic factor of ADNSHL. Few studies have investigated the association between hearing impairment and the variant c.546C>G of KCNQ4. Here, we investigated the phenotype and clinical manifestations of the KCNQ4 variant. Study subjects were selected from the participants of the...

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Identifiers

PMID: 34828318
DOI: 10.3390/genes12111711
PMCID: PMC8618107

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