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Haptoglobin and Its Related Protein, Zonulin—What Is Their Role in Spondyloarthropathy?

8 Mar 2021

Abstract excerpt

Haptoglobin (Hp) is an acute phase protein which supports the immune response and protects tissues from free radicals. Its concentration correlates with disease activity in spondyloarthropathies (SpAs). The Hp polymorphism determines the functional differences between Hp1 and Hp2 protein products. The role of the Hp polymorphism has been demonstrated in many diseases. In particular, the Hp 2-2 phenotype has been...

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PMID: 33800376
DOI: 10.3390/jcm10051131

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