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Article

Contributions from resting state functional connectivity and familial risk to early adolescent-onset MDD: Results from the Adolescent Brain Cognitive Development study.

Journal of affective disorders - 15 May 2021

Cai Yuqi, Elsayed Nourhan M, Barch Deanna M

Abstract excerpt

BACKGROUND: Family history of Major Depressive Disorder (MDD) is a robust predictor of MDD onset, especially in early adolescence. We examined the relationships between familial risk for depression and alterations to resting state functional connectivity (rsFC) within the default mode network (wDMN) and between the DMN and the left/right hippocampus (DMN-LHIPP/DMN-RHIPP) to the risk for early adolescent MDD...

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Identifiers

PMID: 33799042
DOI: 10.1016/j.jad.2021.03.031

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