Article
The Genetic Basis of Delayed Puberty.
Neuroendocrinology - 1 Jan 2018
Howard Sasha R, Dunkel Leo
Abstract excerpt
The genetic control of puberty remains an important but mostly unanswered question. Late pubertal timing affects over 2% of adolescents and is associated with adverse health outcomes including short stature, reduced bone mineral density, and compromised psychosocial health. Self-limited delayed puberty (DP) is a highly heritable trait, which often segregates in an autosomal dominant pattern; however, its...
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