Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish.

Frontiers in endocrinology - 1 Jan 2021

Wu Xin-Jun, Williams Marcus Jermaul, Kew Kimberly Ann, Converse Aubrey, Thomas Peter, Zhu Yong

Abstract excerpt

The role G-protein coupled estrogen receptor (GPER) plays in vertebrate reproduction remains controversial. To investigate GPER's reproductive role, we generated a gper zebrafish mutant line (gper-/- ) using TALENs. Gper mutant females exhibited reduced fertility with a 40.85% decrease in embryo production which was associated with a significant decrease in the number of Stage V (730-750 μm) ovulated oocytes....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogens
Share to Fishes
Share to Metabolomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ovarian Follicle

Share to Ovulation

Share to Receptors, Estrogen

Share to Receptors, G-Protein-Coupled

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33790865
DOI: 10.3389/fendo.2021.637691
PMCID: PMC8006473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish.PMID 33790865Read ↗

G Protein-Coupled Estrogen Receptor Is Not Required for Sex Determination or Ovary Function in Zebrafish.Semantic proximity Read ↗

Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female ZebrafishSemantic proximity Read ↗

Identification of a Membrane Estrogen Receptor in Zebrafish with Homology to Mammalian GPER and Its High Expression in Early Germ Cells of the Testis1Semantic proximity Read ↗

Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish OvarySemantic proximity Read ↗

Establishment of estrogen receptor 1 (ESR1)‐knockout medaka: <scp>ESR</scp>1 is dispensable for sexual development and reproduction in medaka, <i>Oryzias latipes</i>Semantic proximity Read ↗

G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish.Semantic proximity Read ↗

Nuclear Progestin Receptor (Pgr) Knockouts in Zebrafish Demonstrate Role for Pgr in Ovulation but Not in Rapid Non-Genomic Steroid Mediated Meiosis ResumptionSemantic proximity Read ↗

Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesisSemantic proximity Read ↗

Gene knockout analysis reveals essentiality of estrogen receptor β1 (Esr2a) for female reproduction in medakaSemantic proximity Read ↗

Estrogen Receptor Knockout Mice and Their Effects on FertilitySemantic proximity Read ↗

Disruption of Thyroid Hormone Receptor Thrab Leads to Female Infertility in Zebrafish.Semantic proximity Read ↗

Loss of the glucocorticoid receptor causes accelerated ovarian ageing in zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.