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Article

Establishment of estrogen receptor 1 (ESR1)‐knockout medaka: <scp>ESR</scp>1 is dispensable for sexual development and reproduction in medaka, <i>Oryzias latipes</i>

1 Aug 2017

Abstract excerpt

Estrogens play fundamental roles in regulating reproductive activities and they act through estrogen receptor (ESR) in all vertebrates. Most vertebrates have two ESR subtypes (ESR1 and ESR2), whereas teleost fish have at least three (Esr1, Esr2a and Esr2b). Intricate functionalization has been suggested among the Esr subtypes, but to date, distinct roles of Esr have been characterized in only a limited number of...

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PMID: 28782810
DOI: 10.1111/dgd.12386

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