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Article

Single-cell mRNA profiling reveals transcriptional heterogeneity among pancreatic circulating tumour cells

31 May 2017

Abstract excerpt

BACKGROUND: Single-cell mRNA profiling of circulating tumour cells may contribute to a better understanding of the biology of these cells and their role in the metastatic process. In addition, such analyses may reveal new knowledge about the mechanisms underlying chemotherapy resistance and tumour progression in patients with cancer. METHODS: Single circulating tumour cells were isolated from patients with...

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PMID: 28569190
DOI: 10.1186/s12885-017-3385-3

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