How array design creates SNP ascertainment bias.

Abstract excerpt

Single nucleotide polymorphisms (SNPs), genotyped with arrays, have become a widely used marker type in population genetic analyses over the last 10 years. However, compared to whole genome re-sequencing data, arrays are known to lack a substantial proportion of globally rare variants and tend to be biased towards variants present in populations involved in the development process of the respective array. This...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetics, Population
• Share to Algorithms
• Share to Chickens