Article
Altered Antibody Response to Epstein-Barr Virus in Patients With Rheumatoid Arthritis and Healthy Subjects Predisposed to the Disease. A Twin Study.
Frontiers in immunology - 1 Jan 2021
Svendsen Anders J, Westergaard Marie Christine Wulff, Draborg Anette Holck, Holst René, Kyvik Kirsten O, Jakobsen Marianne A, Junker Peter, Houen Gunnar
Abstract excerpt
Objectives: To study Epstein-Barr virus (EBV) antibody patterns in twin individuals with rheumatoid arthritis (RA) and their healthy co-twins, and to determine the heritability of antibody responses against the EBV encoded EBNA1 protein. Methods: Isotypes of EBNA1 antibodies were measured in 137 RA affected- and 150 healthy twin pairs. We estimated the effect of RA and RA predisposition, anti-citrullinated...
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