Article
Increased sCD163 and sCD14 Plasmatic Levels and Depletion of Peripheral Blood Pro-Inflammatory Monocytes, Myeloid and Plasmacytoid Dendritic Cells in Patients With Severe COVID-19 Pneumonia.
Frontiers in immunology - 1 Jan 2021
Zingaropoli Maria Antonella, Nijhawan Parni, Carraro Anna, Pasculli Patrizia, Zuccalà Paola, Perri Valentina, Marocco Raffaella, Kertusha Blerta, Siccardi Guido, Del Borgo Cosmo, Curtolo Ambrogio, Ajassa Camilla, Iannetta Marco, Ciardi Maria Rosa, Mastroianni Claudio Maria, Lichtner Miriam
Abstract excerpt
Background: Emerging evidence argues that monocytes, circulating innate immune cells, are principal players in COVID-19 pneumonia. The study aimed to investigate the role of soluble (s)CD163 and sCD14 plasmatic levels in predicting disease severity and characterize peripheral blood monocytes and dendritic cells (DCs), in patients with COVID-19 pneumonia (COVID-19 subjects). Methods: On admission, in COVID-19...
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