Article
Comprehensive genomic profiling of metastatic collecting duct carcinoma, renal medullary carcinoma, and clear cell renal cell carcinoma.
Urologic oncology - 1 Jun 2021
Bratslavsky Gennady, Gleicher Stephanie, Jacob Joseph M, Sanford Thomas H, Shapiro Oleg, Bourboulia Dimitra, Gay Laurie M, Andrea Elvin Julie, Vergilio Jo-Anne, Suh James, Ramkissoon Shakti, Severson Eric Allan, Killian Jonathan Keith, Schrock Alexa Betzig, Chung Jon H, Miller Vincent A, Mollapour Mehdi, Ross Jeffrey S
Abstract excerpt
INTRODUCTION AND OBJECTIVE: Unlike clear cell renal cell carcinoma (CCRCC), collecting duct carcinoma (CDC) and renal medullary carcinoma (RMC) are rare tumors that progress rapidly and appear resistant to current systemic therapies. We queried comprehensive genomic profiling to uncover opportunities for targeted therapy and immunotherapy. MATERIAL AND METHODS: DNA was extracted from 40 microns of formalin-fixed,...
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