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Article

Macrophage beta2-adrenergic receptor is dispensable for the adipose tissue inflammation and function.

Molecular metabolism - 1 Jun 2021

Petkevicius Kasparas, Bidault Guillaume, Virtue Sam, Newland Stephen A, Dale Martin, Dugourd Aurelien, Saez-Rodriguez Julio, Mallat Ziad, Vidal-Puig Antonio

Abstract excerpt

OBJECTIVE: Neuroimmune interactions between the sympathetic nervous system (SNS) and macrophages are required for the homeostasis of multiple tissues, including the adipose tissue. It has been proposed that the SNS maintains adipose tissue macrophages (ATMs) in an anti-inflammatory state via direct norepinephrine (NE) signaling to macrophages. This study aimed to investigate the physiological importance of this...

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Share to Adipocytes
Share to Adipose Tissue, White

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Marrow Transplantation

Share to Diet, High-Fat

Share to Diet, Western

Share to Panniculitis

Share to Receptors, Adrenergic, beta-2

Share to Sympathetic Nervous System

Source

Open in PubMed Open full text

Identifiers

PMID: 33774223
DOI: 10.1016/j.molmet.2021.101220
PMCID: PMC8086137

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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